Phenylpropanolamine (PPA) occurs as drug of the phenethylamine family used inside bronchial and nasal decongestants, and as well as an appetite suppressant. There are quatern optical isomers of phenylpropanolamine: d- & l-norephedrine, & d- and l-norpseudoephedrine. D-norpseudoephedrine is also referred to as cathine, and occurs naturally in the stimulant plant Catha edulis (khat). This isomer is usually utilized around European medications described as "phenylpropanolamine", whereas in the United States a racemic mixture of d,l-norephedrine is usual. The scientific survey (Kernan et al. 2000) uncovered an increased chance of hemorrhagic stroke in women who utilized phenylpropanolamine, although these are non clear which isomer is to blame. a learn at the Yale University School of Medicine within 1999 had produced similar results. Reports of subjects of haemorrhagic stroke around PPA users got been circulating since a Seventies. Within November 2000, the FDA issued a public health consultive against a utilize of the drug. A professional estimates that PPA driven between 200 & 500 strokes a month among 18-to-49-year-old users. An item on the agenda of the 2000 Commission on Narcotic Drugs session called for including norephedrine inside Table I personally of United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances[http://www.unodc.org/unodc/en/document_1999-12-21_1.html].

See Also
phenethylamines ephedrine pseudoephedrine cathinone methcathinone amphetamine methamphetamine